Multiple Choice QuestionsWhich of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes?
Retrovirus
Ti plasmid
pBR 322
λ phage
A.
Retrovirus
Retrovirus is commonly used as vector for introducing a DNA fragment in human lymphocyte.
Gene therapy: Lymphocyte from the blood of the patient are grown in culture outside the body, a functional gene is introduced by using a retroviral vector, into these lymphocyte.
AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?
AGGUAUCGCAU
UGGTUTCGCAT
UCCAUAGCGUA
ACCUAUGCGAU
A.
AGGUAUCGCAU
Coding strand and mRNA has same nucleotide sequence except, ‘T’ – Thymine is replaced by ‘U’–Uracil in mRNA.
The experimental proof for semiconservative replication of DNA was first shown in a
Fungus
Bacterium
Virus
Plant
B.
Bacterium
Semi-conservative DNA replication was first shown in Bacterium Escherichia coli by Matthew Meselson and Franklin Stahl.
Which of the following is true for nucleolus?
Larger nucleoli are present in dividing cells
It is a membrane-bound structure
It is a site for active ribosomal RNA synthesis
It takes part in spindle formation
C.
It is a site for active ribosomal RNA synthesis
The nucleolus is a non-membranous structure and is a site of r-RNA synthesis.
Select the correct match
Ribozyme - Nucleic acid
F2 × Recessive parent - Dihybrid cross
G. Mendel - Transformation
T.H. Morgan - Transduction
A.
Ribozyme - Nucleic acid
A ribozyme is a catalytic RNA, which is a nucleic acid.
Many ribosomes may associate with a single mRNA to form multiple copies of a polypeptide simultaneously. Such strings of ribosomes are termed as
Polysome
Polyhedral bodies
Nucleosome
Plastidome
A.
Polysome
The phenomenon of association of many ribosomes with single m-RNA leads to the formation of polyribosomes or polysomes or ergasomes.
Which of the following pairs is wrongly matched?
Starch synthesis in pea: Multiple alleles
ABO blood grouping: Co-dominance
T.H. Morgan: Linkage
XO type sex determination: Grasshopper
A.
Starch synthesis in pea: Multiple alleles
Starch synthesis in pea is controlled by a pleiotropic gene.
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