O2 is formed in mesophyll cells while Rubisco is present in bundle sheath cells. Therefore Rubisco does not come in contact with O2 and is thus not affected by it.
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What is stroma ?
Stroma is matrix or the cytoplasm of chloroplast where dark reaction of photosynthesis takes place.
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For which type of plants availability of CO2 is limiting factor ?
C3 plants.
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What are grana ?
Grana are the stacks of thylakoids embedded in the stroma of a chloroplast. They are the sites of light reaction of photosynthesis.