How Bt toxin causes death of insect ?

Bt Toxin when ingested by the insect get converted to active form because of the alkaline pH of the insect gut .Activated Bt toxin binds to the surface of midgut epithelial cells and creates pores that causes cell swelling and lysis which finally leads to death of insect.
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Name two diseases that can be treated by producing biological compound in transgenic animal.


Two diseases that can be treated by producing biological compond in transgenic animal are -
1. Emphysema.
2. Cystic fibrosis.
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How is inactive Bt-toxin converted into active form ?

 When Bt Toxin is ingested by the insect the inactive toxin is converted into active form due to alkaline pH of gut which solubilizes the crystal.
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What is the utility of Bt-Toxin gene ?

Bt-Toxin gene provide Bt-toxin which is involved in providing insect resistance to cotton plant when incorporated in its genome.
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Name a few forms of cry gene.

Few forms of cry gene are Cry IAC, Cry II Ab.
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