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Molecular Basis of Inheritance

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In the DNA molecule

• the  total amount of purine nucleotides and pyrimidine nucleotides is not always equal

• there are two strands, which run parallel in the 5' →3' direction

• the proportion of adenine in relation to thymine varies with organism

• the are two strands, which run antiparallel-one in 5'-3' direction and other in 3' →5'

D.

the are two strands, which run antiparallel-one in 5'-3' direction and other in 3' →5'

In DNA molecule the adjacent deoxyribonucleotides are joined in a chain by phosphodiester bridges or bonds, which link the 5' carbon of deoxyribose of one mononucleotide unit with 3' carbon of deoxyribose of next mononucleotide unit, According to Waston and Crick DNA molecule consists of two such polynucleotide chains wrapped helically around each other, with the sugar-phosphate chain on the outside and purine and pyrimidine on the inside of helix. Two strands run antiparallel, ie, one strand have phosphodiester linkage in 3'→5' direction while another strand has phosphodiester linkage in 5' →3' direction.

Chargaff (1950) suggested that despite wide compositional variations exhibited by different types of DNA the total amount of purines equalled the total amount of purines equaled the total amount of pyrimidines (A + G = T + C)

In DNA molecule the adjacent deoxyribonucleotides are joined in a chain by phosphodiester bridges or bonds, which link the 5' carbon of deoxyribose of one mononucleotide unit with 3' carbon of deoxyribose of next mononucleotide unit, According to Waston and Crick DNA molecule consists of two such polynucleotide chains wrapped helically around each other, with the sugar-phosphate chain on the outside and purine and pyrimidine on the inside of helix. Two strands run antiparallel, ie, one strand have phosphodiester linkage in 3'→5' direction while another strand has phosphodiester linkage in 5' →3' direction.

Chargaff (1950) suggested that despite wide compositional variations exhibited by different types of DNA the total amount of purines equalled the total amount of purines equaled the total amount of pyrimidines (A + G = T + C)

How many nucleotides are present in a bacteriophage $\mathrm{\varphi }$ x 174.

5386

List the function of RNA.

Functions of RNA
RNA acts as genetic material in viruses
It also functions as an adapter and messenger
It also acts as a catalytic molecule and catalyses various biochemical reactions.

List the number of base pairs in :

(i) lambda bacteriophage

(ii) E.coli and

(iii) haploid content of human DNA.

(i) 48502 bp
(ii) 4.6 x 106 bp and
(iii) 3.3 x 109 bp.

Name the genetic material for majority of organisms.

DNA (Deoxyribose nucleic acid)

Comment two chains of DNA have antiparallel polarity.

The Two chain of DNA are antiparallel that is
if one chain has 5’ x 3’ polarity the other chain has 3’ x 5’ polarity.

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