Multiple Choice Questions

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Haemophilia is more commonly seen in human males than in human females because

  • this disease is due to an X- linked dominant mutation

  • a greater proportion of girls die in infancy

  • this disease is due to an X- linked recessive mutation

  • this disease is due to a Y- linked recessive mutation


C.

this disease is due to an X- linked recessive mutation

Haemophilia is a hereditary (recessive X- linked) disease caused due to fault in genes, controlling the factors VIII and IX, on X chromosome. 

Males have one X and Y chromosome each. Y chromosome does not carry any gene for blood clotting. Therefore, this condition is usually seen in males as they carry only one faulty X chromosome.

Females are generally the carrier of the disease as in females, two faulty X- chroromsomes are needed to cause the disease.


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G-6-P dehydrogenase deficiency is associated with haemolysis of

  • lymphocytes

  • RBCs

  • platelets

  • leucocytes


Which of the following substances, if introduce in the blood stream, would cause coagulation, at the site of its introduction?

  • Fibrinogen

  • Prothrombin

  • Heparin

  • Thromboplastin


Heparin is secreted by

  • mast cell

  • alveolar cell

  • plasma cell

  • goblet cell


In diastole, heart is filled by

  • mixed blood

  • venous blood

  • oxygenated blood

  • deoxygenated blood


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The first heart sound is produced when

  • diastole begins

  • semilunar valve close quickly

  • interventricular pressure decrease

  • bicuspid and tricuspid valve close quickly


The epithelial lining in the alveoli of the frogs facing lung cavity is

  • squamous ciliated

  • columnar ciliated

  • columnar nonciliated

  • squamous nonciliated


RBC's are nucleated in

  • man

  • rat

  • frog

  • rabbit


CO is harmful to human being because

  • it decreases CO2 concentration

  • it competes O2 to combine with haemoglobin

  • it is carcinogenic

  • it depletes O2 layer


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Which vertebrate orgen receives only oxygenated blood?

  • Gill

  • Lung

  • Spleen

  • Liver


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