Gene therapy can be used to correct hereditary diseases. It involves delivery of a normal gene into the individual or embryo to take over the function of and compensate for the non-functional gene.
The first clinical gene therapy was given in 1990 to a 4-year old girl with adenosine deaminase (ADA) deficiency. In this disease, the gene coding for enzyme ADA gets deleted leading to deficiency of ADA and problems in immune system. Gene therapy for ADA deficiency includes isolation of lymphocytes from patient’s blood, culturing them in-vitro, introduction of functional ADA cDNA and returning the cells to the patient’s body.
Write the scientific names of the causal organisms of elephantiasis and ringworm in humans. Mention the body parts affected by them.
Study the graph given below. Explain how oxygen concentration is affected in the river when sewage is discharged into it.
