How the enzymes speed up the rate of reaction ?
The enzymes speed up the rate of reaction by lowering the activation energy of substrate . They form enzyme substrate complex. The binding lowers the activation energy.
Enzymes bring down the energy barrier between a substrate and the product making the reaction easy and fast. Lower the activation energy higher will be the rate of reaction and higher the activation energy lower will be the rate of reaction.
Enzymes can accelerate reactions by:
i. stabilizing the transition state (substrate+enzyme complex) of a reaction.
ii. providing an alternative reaction pathway for a biological reaction.
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