Proteins have primary structure. If you are given a method to know which amino acid is at either of the two termini (ends) of a protein, can you connect this information to purify or homogeneity of a protein?
Yes, the arrangement of amino acids ie. the positional information in a protein-which is the first amino acid, which is second, and so on is called the primary structure of a protein. The primary structure is very necessary for the proper functioning of the protein because the sequence of amino acids are used as a code for the synthesis of different protein. Any change in the primary structure will give rise to a incorrect protein. Therefore if we know the sequence of a particular protein we can check the purity by comparing its sequence to the known sequence by experimental method.
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