During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure, what is it’s DNA-binding sequence?
TTAA
AATT
CACC
CACC
D.
CACC
TATA box is present in eukaryotic promotor region. It has a resemblance with pribnow box of prokaryotes. TATA box was identified by Dr. Hogness and so, it is called as Hogness box. It is a 7 bp long region located 20 bp upstream to the start point. During the process of transcription the RNA polymerase (a holoenzyme which has a core unit and sigma factor for proper initiation of transcription) binds to TATA box due to which DNA assumes a saddle-like structure at this place.
Telomere repetitive DNA sequences control the function of eukaryotic chromosomes because they
act as replicons.
are RNA transcription initiator
help chromosome pairing
help chromosome pairing
Differentiation of organs and tissues in a developing organism, is associated with
developmental mutations
differential expression of genes
lethal mutations
lethal mutations
Molecular basis of organ differentiation dpends on the modulation in transcription by
RNA polymerase
ribosome
transcription factor
transcription factor
The linking of antibiotic resistance gene with the plasmid vector became possible with
DNA ligase
endonucleases
DNA polymerase
DNA polymerase