What triggers activation of protoxin to active Bt toxin of Bacill

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 Multiple Choice QuestionsMultiple Choice Questions

211.

Select the wrong statement

  • Human insulin is being commercially produced from a transgenic species of Escherichia coli.

  • The genetically modified bacillus thuringiensis is used as biopesticide on the commercial scale

  • Human protein, alpha-1 -antitrypsin is used to treat emphysema

  • The first transgenic cow, Rosie, produced alpha lactalbumin, enriched milk

  • The first transgenic cow, Rosie, produced alpha lactalbumin, enriched milk


212.

Which one of the following is used extensively in biochemical and genetic work?

  • Saccharomyces

  • Aspergillus

  • Claviceps

  • Penicillium

  • Penicillium


213.

Which of the following statements about transgenic animals is/are false?

(i) Transgenic animals are designed to study how genes are regulated.

(ii) They are specially made to serve as models for human diseases.

(iii) Transgenic Cow, Rosie was created to produce the human protein a-1-antitrypsin.

(iv) Transgenic mice are used to test the safety of vaccines.

  • (iii) only

  • (i) and (iii) only

  • (ii) only

  • (ii) and (iii) only

  • (ii) and (iii) only


214.

Which of the following glucose transporters is insulin-dependent?

  • GLUT II

  • GLUT III

  • GLUT IV

  • GLUT I


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215.

What triggers activation of protoxin to active Bt toxin of Bacillus thuringiensis in boll worm?

  • Moist surface of midgut

  • Alkaline pH of gut

  • Acidic pH of stomach

  • Body temperature


B.

Alkaline pH of gut

Bacillus thuringiensis forms protein crystals during a particular phase of their growth. These crystals contain a toxic insecticidal protein. These protein exist as inactive protoxins but once an insect ingest the inactive toxin, it is converted into an active form of toxin due to alkaline pH of the gut which solubilize the crystals. The activated toxin binds to the surface of midgut epithelial cells and create pores that cause cell swelling and lysis and eventually cause death of insect.


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216.

Which of the following is true for Golden rice?

  • It is pest resistant, with a gene from Bacillus thuringiensis

  • It is drought tolerant, developed using Agrobacterium vector

  • It has yellow grains, because of a gene introduced from a primitive variety of rice

  • It is Vitamin A enriched, with a gene from daffodil


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