2. Sporozoites are the infective stage. which enter the body, reach the liver through blood and multiply within the liver cells.
3. Infected liver cells burst and release the parasites (Cryptomerozoites) into blood which then attack RBCs. They multiply with RBCs and cause their rupture.
4. The rupture of RBCs releases a toxin called haemozoin, which is responsible for the high recurring fever and the chill/ shivering .
5.The parasite then enters the female Anopheles mosquito along with the blood when it bites the infected person.
6. Further development occurs in the stomach of the mosquito. They multiply and are stored in salivary glands
7. Sporozoites formed are transported to and stored in the salivary glands of mosquitoes and are transferred to a human body during the bite of the mosquito.