1. Cellular respiration uses oxygen while fermentation does not require oxygen.
2. Cellular respiration produces 38 ATP, while fermentation produces only 2 ATP.
3. Cellular respiration is more efficient than fermentation in the generation of ATP.
4. In aerobic respiration the glucose is completely broken down into carbondioxide and water. While in fermentation the glucose is partialy broken down into carbon dioxide and ethanol/lactic acid.