Explain Central Dogma of flow of information. from Biology Molecu

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51.

Explain Central Dogma of flow of information.


Central Dogma.

It is the flow of information from DNA to mRNA (transcription) and then decoding information present in mRNA in the formation of polypeptide chain or protein (Translation). It was proposed by Crick 1958.

Replication

In other words, the four letter language of DNA is transcribed into 4 letter language of mRNA in the form of triplet (codons) which is then translated in 20 letter language of protein. The structural proteins form the protoplasm whereas functional proteins constitute the enzyme, hormones, interferons and antibodies. Thus DNA directs various characters in the form of synthesis of a particular protein.

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52.

Give a schematic structure of transcription unit.

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53. Explain briefly transcription.
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54. What are retroviruses ? How has their discovery led to the modification of central dogma in molecular biology ?
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55. What is retrovirus ?
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56. What is genetic code ? List the properties of genetic code.
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57. What is RNA polymerase ? Write its functions.
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58.

What is the full form of VNTR

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59. Suppose during transcription of DNA code AAA, a mistake occurs due to which UUG code of RNA is formed. Due to this what change in picking the type of amino acid would occur during synthesis of protein.
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60. What is the role of AUG?
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