(a) Why is human ABO blood group gene considered a good example of multiple alleles?
(b) Work out a cross up to F1 generation only, between a mother with blood group A (Homozygous) and the father with blood group B (Homozygous). Explain the pattern of inheritance exhibited.
(a) ABO blood group is considered a good example of multiple alleles as it is controlled by I gene which has 3 alleles IA, IB and i. The three alleles govern the same character and hence show multiple allelism.
(b) Homozygous mother having blood group A will have a genotype of- IAIA
Homozygous father having blood group B will have a genotype of- IBIB
A cross between
Thus the progeny will havethe blood group AB (genotype IAIB) as the alleles A and B are co-dominant to each other that is they express themselves independently even in the presence of other. Thus the progeny resembles both the parents. The pattern of inheritance is called co-dominance pattern of inheritance.
A child by the family from Thalassemia is born to a normal couple. But the mother is being blamed by the family for delivering a sick baby. (a) What is Thalassemia?
(b) How would you counsel the family not to blame the mother for delivering a child suffering from this disease? Explain.
(c) List the values your counseling can propagate in the families.A garden pea plant (A) produced inflated yellow pod, and another plant (B) of the same species produced constricted green pods. Identify the dominant traits.
What is the inheritance pattern observed in the size of starch grains and seed shape of Pisum sativum? Workout the monohybrid cross showing the above traits. How does this pattern of inheritance deviate from that of Mendelian law of dominance?
(a) Sickle celled anaemia in humans is a result of point mutation. Explain.
(b) Write the genotypes of both the parents who have produced a sickle celled anaemic offspring.
How many chromosomes do drones of honeybee possess? Name the type of cell division involved in the production of sperms by them.
During a monohybrid cross involving a tall pea plant with a dwarf pea plant, the offspring populations were tall and dwarf in equal ratio. Work out a cross to show how is it possible.
(a) Why are thalassemia and haemophilia categorized as Mendelian disorders ? Write the symptoms of these diseases. Explain their pattern of inheritance in humans.
(b) Write the genotypes of the normal parents producing a haemophilic son.