(a) Why is human ABO blood group gene considered a good example of multiple alleles?
(b) Work out a cross up to F1 generation only, between a mother with blood group A (Homozygous) and the father with blood group B (Homozygous). Explain the pattern of inheritance exhibited.
A child by the family from Thalassemia is born to a normal couple. But the mother is being blamed by the family for delivering a sick baby. (a) What is Thalassemia?
(b) How would you counsel the family not to blame the mother for delivering a child suffering from this disease? Explain.
(c) List the values your counseling can propagate in the families.A garden pea plant (A) produced inflated yellow pod, and another plant (B) of the same species produced constricted green pods. Identify the dominant traits.
What is the inheritance pattern observed in the size of starch grains and seed shape of Pisum sativum? Workout the monohybrid cross showing the above traits. How does this pattern of inheritance deviate from that of Mendelian law of dominance?
The starch synthesis in pea plants is controlled by a single gene. It has two alleles B and b. BB homozygotes produce starch effectively and therefore produce large starch grains. Whereas the bb homozygotes are less efficient in starch production and hence produce smaller grains. After maturation the BB seeds were found to be round and bb was wrinkled. Heterozygotes produce round seeds, and so B was considered to be the dominant allele. But when they were crossed the resultant progeny were intermediate-sized Bb seeds.
P generation BB × bb
↓
F1 Generation Bb × Bb
|
B |
b |
B |
BB (long grains) |
Bb (intermediate grains) |
b |
Bb (intermediate grains) |
bb (small grains)
|
(a) Sickle celled anaemia in humans is a result of point mutation. Explain.
(b) Write the genotypes of both the parents who have produced a sickle celled anaemic offspring.
How many chromosomes do drones of honeybee possess? Name the type of cell division involved in the production of sperms by them.
During a monohybrid cross involving a tall pea plant with a dwarf pea plant, the offspring populations were tall and dwarf in equal ratio. Work out a cross to show how is it possible.
(a) Why are thalassemia and haemophilia categorized as Mendelian disorders ? Write the symptoms of these diseases. Explain their pattern of inheritance in humans.
(b) Write the genotypes of the normal parents producing a haemophilic son.