In a cross between two tall pea plants some of the off-springs produced were dwarf. Show with the help of Punnett square how this is possible.
A student on a school trip started sneezing and wheezing soon after reaching the hill station for no explained reasons. But, on return to the plains, the symptoms disappeared. What is such a response called? How does the body produce it?
Write the function of adenosine deaminase enzyme. State the cause of ADA deficiency in humans. Mention a possible permanent cure for ADA deficiency patient.
Adenosine deaminase enzyme is very important for the functioning of immune system. ADA deficiency is due to deletion of the gene for adenosine deaminase.
Possible permanent cure for the deficiency is gene therapy. In gene therapy the lymphocytes from the blood of the patients are grown in a culture outside the body. Then a functional ADA cDNA using a retroviral vector is introduced into the cultured lymphocytes. The lymphocytes are then returned to the patient’s body. If the genes isolated from the bone marrow cells producing ADA is introduced into the cells at an early embryonic stage the cure can be permanent.(a) Mention the difference in the mode of action of exonuclease and endonuclease.
(b)How does restriction endonuclease function?Draw a diagram of the microscopic structure of human sperm. Label the following parts in it and write their functions.
(a) Acrosome
(b) Nucleus
(c) Middle piece