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Molecular Basis of Inheritance

Short Answer Type

41. Write differences between Prokaryotic DNA and Eukaryotic DNA.

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42.

Differentiate between the followings:
(a) Repetitive DNA and Satellite DNA
(b) mRNA and tRNA
(c) Template strand and Coding strand

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43. Which property of DNA double helix led Watson and Crick to hypothesize semi-conservative mode of DNA replication ? Explain.

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44. Differentiate Leading Strand and Lagging Strand.

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Long Answer Type

45.

Sketch and explain clover leaf model of tRNA.

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One Word Answers

46. Who developed DNA fingerprinting technique.

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Short Answer Type

47. Write a note on repair replication.

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48.
Write a note on messenger RNA.

Messenger RNA (mRNA)

It forms only 5% of total RNA but is longest of all. It brings instructions from DNA for the formation of a particular polypeptide. The instructions are coded in the form of base sequence called genetic code. Three adjacent nitrogen bases specify a particular amino acid. Formation of polypeptides occur over the ribosomes. mRNA gets attached to ribosomes.

mRNA.

It starts as a cap for attachment with ribosome. It is followed by initiation codon (AUG) either immediately or after a small non-coding region. It is followed by coding region followed by termination codon (UAA, UAG and UGA). Then there is a small non-coding region and poly A area at 3 terminus. The mRNA may specify only a single polypeptide or number of them called monocistronic and polycistronic respectively.

Life span of mRNA may be a few minutes to an hour or even days in case of RBC.

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