(a) What do 'Y' and 'B' stand for in 'YAC' and 'BAC' used in Human Genome Project (HGP). Mention their role in the project.
(b) Write the percentage of the total human genome that codes for proteins and the percentage of discovered genes whose functions are known as observed during HGP.
(c) Expand 'SNPs' identified by scientists in HGP.
(a) Name the stage in the cell cycle where DNA replication occurs.
(b) Explain the mechanism of DNA replication. Highlight the role of enzymes in the process.
(c) Why is DNA replication said to be semiconservative ?
Describe the experiment that helped demonstrate the semi-conservative mode of DNA replication
(a) How are the following formed and involved in DNA packaging in a nucleus of a cell?
(b) Differentiate between Euchromatin and Heterochromatin
Mention the contribution of genetic maps in human genome project.
The contribution of genetic maps in human genome project.
1. The gene mapping has made it possible to sequence the whole human genome.
2. Genetic maps have been used to find the exact chromosomal location.
3. The distances between markers and genes could be measured using the gentic maps.
A. Name the enzyme that catalyses the transcription of hnRNA.
B. Why does the hnRNA need to undergo changes ? List the changes hnRNA undergoes and where in the cell such changes take place.
Unambiguous, universal and degenerate are some of the terms used for the genetic code. Explain the salient features of each one of them.
A number of passengers were severely burnt beyond recognition during a train accident. Name and describe a modern technique that can help hand over the dead to their relatives.